Tricuspid Regurgitation, the Forgotten Valvular Lesion—A Contemporary Review of Etiology, Prevalence, and Management Options
Richard Cheng, MD, Amir Azarbal, MD, Jesse Currier, MD, Louise E. J. Thomson, MBChB, FRACP, Michele A. Hamilton, MD, Fardad Esmailian, MD, Babak Azarbal, MD
In this article, the etiology, risk factors, associated disease conditions for tricuspid regurgitation, as well as diagnostic modalities available for the diagnosis of this condition, are explored. Current treatment modalities, including indications for medical versus surgical therapy, as well as emerging surgical and percutaneous options, are discussed.
Targeting the Papillary Muscles in Mitral Valve Repair for Ischemic Mitral Regurgitation
Christos G. Mihos, DO, Andres M. Pineda, MD, Orlando Santana, MD
Ischemic mitral regurgitation due to left ventricular remodeling and leaflet tethering is associated with decreased survival, and the optimal management remains unknown. Restrictive mitral annuloplasty is the current treatment of choice, but it is associated with a 15% to 30% incidence of late recurrent mitral regurgitation, which confers a poor prognosis. A pathophysiology-guided approach to surgical repair is preferable, with a goal of alleviating leaflet tethering and restoring proper subvalvular mechanics. In patients with preoperative predictors of annuloplasty failure, combining a papillary muscle repositioning technique with conventional annuloplasty repair allows for complete geometric repair of the ventriculomitral unit.
Heparin: Physiology, Pharmacology, and Clinical Application
Michael S. Lee, MD, Jeremy Kong, BS
This review examines the physiology, pharmacology, therapeutic applications, dosing regimens, and efficacy of heparin in the setting of percutaneous coronary intervention (PCI). In addition, a review of data on addition of glycoprotein IIb/IIIa inhibitors to heparin and comparison of heparin monotherapy to bivalirudin in PCI is included.
Coronary Plaque Characteristics Affect No-Reflow During Primary Percutaneous Coronary Intervention: A Pooled Analysis of 14 Observational Studies Using Intravascular Ultrasound
Bu-Chun Zhang, MD, PhD, Cheng Wang, MD, Zhi-Wen Zhou, MD, PhD, Yan-Feng Ma, MD, Wen-Hua Li, MD, Dong-Ye Li, MD
This pooled analysis combines primary data to produce reliable estimates of the association of coronary plaque composition assessed by intravascular ultrasound with the incidence of no-reflow after percutaneous coronary intervention among patients with acute coronary syndrome.
Flecainide-induced Torsades de Pointes: Case Report and Review of Literature
Mohammad Nasser, MD, Shadi Idris, MD, Kimberly Marinelli, RN, Christian Machado, MD
This case report illustrates a rare but serious proarrhythmic property of flecainide observed particularly in women.
Anomalous Origin of the Right Coronary Artery From the Left Anterior Descending Artery With Anomalous Course Between the Great Vessels: A Case for Conservative Management With Review of the Literature
Prakash Suryanarayana, MD, Shubha Kollampare, MD, Mohammad Reza Movahed, MD
A single left coronary artery is a rare coronary anomaly, and there are only 10 such reported cases in the medical literature to date. In this report, the authors describe a rare case with a detailed review of the literature.
Now available for your iPhone and iPad
Tricuspid Regurgitation, the Forgotten Valvular Lesion—A Contemporary Review of Etiology, Prevalence, and Management Options
Richard Cheng, MD, Amir Azarbal, MD, Jesse Currier, MD, Louise E. J. Thomson, MBChB, FRACP, Michele A. Hamilton, MD, Fardad Esmailian, MD, Babak Azarbal, MD
In this article, the etiology, risk factors, associated disease conditions for tricuspid regurgitation, as well as diagnostic modalities available for the diagnosis of this condition, are explored. Current treatment modalities, including indications for medical versus surgical therapy, as well as emerging surgical and percutaneous options, are discussed.
Targeting the Papillary Muscles in Mitral Valve Repair for Ischemic Mitral Regurgitation
Christos G. Mihos, DO, Andres M. Pineda, MD, Orlando Santana, MD
Ischemic mitral regurgitation due to left ventricular remodeling and leaflet tethering is associated with decreased survival, and the optimal management remains unknown. Restrictive mitral annuloplasty is the current treatment of choice, but it is associated with a 15% to 30% incidence of late recurrent mitral regurgitation, which confers a poor prognosis. A pathophysiology-guided approach to surgical repair is preferable, with a goal of alleviating leaflet tethering and restoring proper subvalvular mechanics. In patients with preoperative predictors of annuloplasty failure, combining a papillary muscle repositioning technique with conventional annuloplasty repair allows for complete geometric repair of the ventriculomitral unit.
Heparin: Physiology, Pharmacology, and Clinical Application
Michael S. Lee, MD, Jeremy Kong, BS
This review examines the physiology, pharmacology, therapeutic applications, dosing regimens, and efficacy of heparin in the setting of percutaneous coronary intervention (PCI). In addition, a review of data on addition of glycoprotein IIb/IIIa inhibitors to heparin and comparison of heparin monotherapy to bivalirudin in PCI is included.
Coronary Plaque Characteristics Affect No-Reflow During Primary Percutaneous Coronary Intervention: A Pooled Analysis of 14 Observational Studies Using Intravascular Ultrasound
Bu-Chun Zhang, MD, PhD, Cheng Wang, MD, Zhi-Wen Zhou, MD, PhD, Yan-Feng Ma, MD, Wen-Hua Li, MD, Dong-Ye Li, MD
This pooled analysis combines primary data to produce reliable estimates of the association of coronary plaque composition assessed by intravascular ultrasound with the incidence of no-reflow after percutaneous coronary intervention among patients with acute coronary syndrome.
Flecainide-induced Torsades de Pointes: Case Report and Review of Literature
Mohammad Nasser, MD, Shadi Idris, MD, Kimberly Marinelli, RN, Christian Machado, MD
This case report illustrates a rare but serious proarrhythmic property of flecainide observed particularly in women.
Anomalous Origin of the Right Coronary Artery From the Left Anterior Descending Artery With Anomalous Course Between the Great Vessels: A Case for Conservative Management With Review of the Literature
Prakash Suryanarayana, MD, Shubha Kollampare, MD, Mohammad Reza Movahed, MD
A single left coronary artery is a rare coronary anomaly, and there are only 10 such reported cases in the medical literature to date. In this report, the authors describe a rare case with a detailed review of the literature.
Now available for your iPhone and iPad
Tricuspid Regurgitation, the Forgotten Valvular Lesion—A Contemporary Review of Etiology, Prevalence, and Management Options
Richard Cheng, MD, Amir Azarbal, MD, Jesse Currier, MD, Louise E. J. Thomson, MBChB, FRACP, Michele A. Hamilton, MD, Fardad Esmailian, MD, Babak Azarbal, MD
In this article, the etiology, risk factors, associated disease conditions for tricuspid regurgitation, as well as diagnostic modalities available for the diagnosis of this condition, are explored. Current treatment modalities, including indications for medical versus surgical therapy, as well as emerging surgical and percutaneous options, are discussed.
Targeting the Papillary Muscles in Mitral Valve Repair for Ischemic Mitral Regurgitation
Christos G. Mihos, DO, Andres M. Pineda, MD, Orlando Santana, MD
Ischemic mitral regurgitation due to left ventricular remodeling and leaflet tethering is associated with decreased survival, and the optimal management remains unknown. Restrictive mitral annuloplasty is the current treatment of choice, but it is associated with a 15% to 30% incidence of late recurrent mitral regurgitation, which confers a poor prognosis. A pathophysiology-guided approach to surgical repair is preferable, with a goal of alleviating leaflet tethering and restoring proper subvalvular mechanics. In patients with preoperative predictors of annuloplasty failure, combining a papillary muscle repositioning technique with conventional annuloplasty repair allows for complete geometric repair of the ventriculomitral unit.
Heparin: Physiology, Pharmacology, and Clinical Application
Michael S. Lee, MD, Jeremy Kong, BS
This review examines the physiology, pharmacology, therapeutic applications, dosing regimens, and efficacy of heparin in the setting of percutaneous coronary intervention (PCI). In addition, a review of data on addition of glycoprotein IIb/IIIa inhibitors to heparin and comparison of heparin monotherapy to bivalirudin in PCI is included.
Coronary Plaque Characteristics Affect No-Reflow During Primary Percutaneous Coronary Intervention: A Pooled Analysis of 14 Observational Studies Using Intravascular Ultrasound
Bu-Chun Zhang, MD, PhD, Cheng Wang, MD, Zhi-Wen Zhou, MD, PhD, Yan-Feng Ma, MD, Wen-Hua Li, MD, Dong-Ye Li, MD
This pooled analysis combines primary data to produce reliable estimates of the association of coronary plaque composition assessed by intravascular ultrasound with the incidence of no-reflow after percutaneous coronary intervention among patients with acute coronary syndrome.
Flecainide-induced Torsades de Pointes: Case Report and Review of Literature
Mohammad Nasser, MD, Shadi Idris, MD, Kimberly Marinelli, RN, Christian Machado, MD
This case report illustrates a rare but serious proarrhythmic property of flecainide observed particularly in women.
Anomalous Origin of the Right Coronary Artery From the Left Anterior Descending Artery With Anomalous Course Between the Great Vessels: A Case for Conservative Management With Review of the Literature
Prakash Suryanarayana, MD, Shubha Kollampare, MD, Mohammad Reza Movahed, MD
A single left coronary artery is a rare coronary anomaly, and there are only 10 such reported cases in the medical literature to date. In this report, the authors describe a rare case with a detailed review of the literature.
Now available for your iPhone and iPad