Taxi Cab Syndrome: A Review of the Extensive Genitourinary Pathology Experienced by Taxi Cab Drivers and What We Can Do to Help
Alon Y. Mass, MD, David S. Goldfarb, MD, Ojas Shah, MD
This review consolidates knowledge regarding the extensive genitourinary pathology experienced by taxi cab drivers. Taxi cab, livery, truck, and other drivers both objectively and subjectively may have more voiding dysfunction, infertility, urolithiasis, bladder cancer, and urinary infections as compared with nondrivers; this is called taxi cab syndrome. Simple interventions such as education, the addition of taxi relief stations, and possibly the use of sanitary urinary collection devices to curb the progression of genitourinary disease in taxi drivers should be prospectively studied. It is postulated that many of these interventions may also benefit other groups of occupationally related infrequent voiders.
Management of Erectile Dysfunction in the Hypogonadal Man: A Case-Based Review
Ranjith Ramasamy, MD, Jason M. Scovell, BBA, Nathan A. Wilken, BS, Jason R. Kovac, MD, Larry I. Lipshultz, MD
The authors utilize clinical vignettes to discuss the appropriate management of two clinical cases of men at different life stages with erectile dysfunction in the setting of hypogonadism and propose a treatment algorithm.
The Emerging Role of Social Media in Urology
Michael J. Leveridge, MD, FRCSC
This article presents an overview of the most recent data on the impact and potential complications of social media usage in the urologic community.
Role of Chemokines in Renal Cell Carcinoma
Jaspreet S. Parihar, MD, Hari S.G.R. Tunuguntla, MD
With new frontiers of pharmaceutical therapies focusing on tumor growth and angiogenesis, understanding the interaction between immune system and tumor microenvironment has become ever more important. As the role of chemokines in renal cancer becomes more evident, further research will lead to a better understanding of tumor biology and the development of new therapeutic targets to help improve survival.
The Rationale for Optimal Combination Therapy With Sipuleucel-T for Patients With Castration-resistant Prostate Cancer
Vladimir Mouraviev, MD, Neil Mariados, MD, David Albala, MD, Raoul S. Concepcion, MD, Neal D. Shore, MD, FACS, Robert B. Sims, MD, Mark Emberton, MD, Christopher M. Pieczonka, MD
Immunotherapy encourages the recipient’s own immune response to destroy cancer cells, and current evidence suggests that immunotherapies may be most beneficial in early metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T is the first therapeutic cancer vaccine to be approved by both the US Food and Drug Administration and European Medicines Agency for the treatment of asymptomatic or minimally symptomatic mCRPC. Combining immunotherapy with other treatments may have potent anticancer effects; cytoreductive therapies can release tumor antigens and promote a proinflammatory environment that could augment immunotherapies. However, some cytoreductive agents or coadministered drugs may be immunosuppressive. Understanding these interactions between different mCRPC treatment modalities may offer further potential to improve patient outcomes.
From the President’s Desk
Juan A. Reyna, MD
Shared Medical Appointments in Urology
Jonathan Rubenstein, MD
Highlights From the 2014 American Urological Association Annual Meeting, May 16-21, 2014, Orlando, FL
Best of the 2014 AUA Annual Meeting
Adam J.M. Kern, MD, Alan W. Partin, MD, PhD, Ellen Shapiro, MD, FACS, FAAP
Occult Renal Cell Carcinoma Manifesting as Nasal Mass and Epistaxis
Janak Singh, MCh (Urology), Vishwas Baheti, MCh (Urology), Sher Singh Yadav, MCh (Urology), Rajeev Mathur, MCh (Urology)
The authors report a case of metastatic renal cell carcinoma presenting with right nasal cavity mass and epistaxis, followed by a brief review of the relevant literature.
Urethral Duplication in a 15-Year-Old: Case Report With Review of the Literature
Mayank Baid, MBBS, MS, Arindam Dutta, MS, MCh (Urology)
Urethral duplication is a rare congenital malformation mainly affecting men and boys. Although a number of theories have been proposed to describe this condition, the actual mechanism of this disorder is still not clear. This article highlights a case of urethral duplication in a 15-year-old boy.
Social Media
Christopher E. Bayne, MD, Declan G. Murphy, MB, BCH, BaO, FRACS, FRCS Urol, Stacy Loeb, MD, MSc
Prostate Cancer
Dara Lundon, MD, Stacy Loeb, MD, MSc
Prostate Cancer
Meena Davuluri, Stacy Loeb, MD, MSc
Taxi Cab Syndrome: A Review of the Extensive Genitourinary Pathology Experienced by Taxi Cab Drivers and What We Can Do to Help
Alon Y. Mass, MD, David S. Goldfarb, MD, Ojas Shah, MD
This review consolidates knowledge regarding the extensive genitourinary pathology experienced by taxi cab drivers. Taxi cab, livery, truck, and other drivers both objectively and subjectively may have more voiding dysfunction, infertility, urolithiasis, bladder cancer, and urinary infections as compared with nondrivers; this is called taxi cab syndrome. Simple interventions such as education, the addition of taxi relief stations, and possibly the use of sanitary urinary collection devices to curb the progression of genitourinary disease in taxi drivers should be prospectively studied. It is postulated that many of these interventions may also benefit other groups of occupationally related infrequent voiders.
Management of Erectile Dysfunction in the Hypogonadal Man: A Case-Based Review
Ranjith Ramasamy, MD, Jason M. Scovell, BBA, Nathan A. Wilken, BS, Jason R. Kovac, MD, Larry I. Lipshultz, MD
The authors utilize clinical vignettes to discuss the appropriate management of two clinical cases of men at different life stages with erectile dysfunction in the setting of hypogonadism and propose a treatment algorithm.
The Emerging Role of Social Media in Urology
Michael J. Leveridge, MD, FRCSC
This article presents an overview of the most recent data on the impact and potential complications of social media usage in the urologic community.
Role of Chemokines in Renal Cell Carcinoma
Jaspreet S. Parihar, MD, Hari S.G.R. Tunuguntla, MD
With new frontiers of pharmaceutical therapies focusing on tumor growth and angiogenesis, understanding the interaction between immune system and tumor microenvironment has become ever more important. As the role of chemokines in renal cancer becomes more evident, further research will lead to a better understanding of tumor biology and the development of new therapeutic targets to help improve survival.
The Rationale for Optimal Combination Therapy With Sipuleucel-T for Patients With Castration-resistant Prostate Cancer
Vladimir Mouraviev, MD, Neil Mariados, MD, David Albala, MD, Raoul S. Concepcion, MD, Neal D. Shore, MD, FACS, Robert B. Sims, MD, Mark Emberton, MD, Christopher M. Pieczonka, MD
Immunotherapy encourages the recipient’s own immune response to destroy cancer cells, and current evidence suggests that immunotherapies may be most beneficial in early metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T is the first therapeutic cancer vaccine to be approved by both the US Food and Drug Administration and European Medicines Agency for the treatment of asymptomatic or minimally symptomatic mCRPC. Combining immunotherapy with other treatments may have potent anticancer effects; cytoreductive therapies can release tumor antigens and promote a proinflammatory environment that could augment immunotherapies. However, some cytoreductive agents or coadministered drugs may be immunosuppressive. Understanding these interactions between different mCRPC treatment modalities may offer further potential to improve patient outcomes.
From the President’s Desk
Juan A. Reyna, MD
Shared Medical Appointments in Urology
Jonathan Rubenstein, MD
Highlights From the 2014 American Urological Association Annual Meeting, May 16-21, 2014, Orlando, FL
Best of the 2014 AUA Annual Meeting
Adam J.M. Kern, MD, Alan W. Partin, MD, PhD, Ellen Shapiro, MD, FACS, FAAP
Occult Renal Cell Carcinoma Manifesting as Nasal Mass and Epistaxis
Janak Singh, MCh (Urology), Vishwas Baheti, MCh (Urology), Sher Singh Yadav, MCh (Urology), Rajeev Mathur, MCh (Urology)
The authors report a case of metastatic renal cell carcinoma presenting with right nasal cavity mass and epistaxis, followed by a brief review of the relevant literature.
Urethral Duplication in a 15-Year-Old: Case Report With Review of the Literature
Mayank Baid, MBBS, MS, Arindam Dutta, MS, MCh (Urology)
Urethral duplication is a rare congenital malformation mainly affecting men and boys. Although a number of theories have been proposed to describe this condition, the actual mechanism of this disorder is still not clear. This article highlights a case of urethral duplication in a 15-year-old boy.
Social Media
Christopher E. Bayne, MD, Declan G. Murphy, MB, BCH, BaO, FRACS, FRCS Urol, Stacy Loeb, MD, MSc
Prostate Cancer
Dara Lundon, MD, Stacy Loeb, MD, MSc
Prostate Cancer
Meena Davuluri, Stacy Loeb, MD, MSc
Taxi Cab Syndrome: A Review of the Extensive Genitourinary Pathology Experienced by Taxi Cab Drivers and What We Can Do to Help
Alon Y. Mass, MD, David S. Goldfarb, MD, Ojas Shah, MD
This review consolidates knowledge regarding the extensive genitourinary pathology experienced by taxi cab drivers. Taxi cab, livery, truck, and other drivers both objectively and subjectively may have more voiding dysfunction, infertility, urolithiasis, bladder cancer, and urinary infections as compared with nondrivers; this is called taxi cab syndrome. Simple interventions such as education, the addition of taxi relief stations, and possibly the use of sanitary urinary collection devices to curb the progression of genitourinary disease in taxi drivers should be prospectively studied. It is postulated that many of these interventions may also benefit other groups of occupationally related infrequent voiders.
Management of Erectile Dysfunction in the Hypogonadal Man: A Case-Based Review
Ranjith Ramasamy, MD, Jason M. Scovell, BBA, Nathan A. Wilken, BS, Jason R. Kovac, MD, Larry I. Lipshultz, MD
The authors utilize clinical vignettes to discuss the appropriate management of two clinical cases of men at different life stages with erectile dysfunction in the setting of hypogonadism and propose a treatment algorithm.
The Emerging Role of Social Media in Urology
Michael J. Leveridge, MD, FRCSC
This article presents an overview of the most recent data on the impact and potential complications of social media usage in the urologic community.
Role of Chemokines in Renal Cell Carcinoma
Jaspreet S. Parihar, MD, Hari S.G.R. Tunuguntla, MD
With new frontiers of pharmaceutical therapies focusing on tumor growth and angiogenesis, understanding the interaction between immune system and tumor microenvironment has become ever more important. As the role of chemokines in renal cancer becomes more evident, further research will lead to a better understanding of tumor biology and the development of new therapeutic targets to help improve survival.
The Rationale for Optimal Combination Therapy With Sipuleucel-T for Patients With Castration-resistant Prostate Cancer
Vladimir Mouraviev, MD, Neil Mariados, MD, David Albala, MD, Raoul S. Concepcion, MD, Neal D. Shore, MD, FACS, Robert B. Sims, MD, Mark Emberton, MD, Christopher M. Pieczonka, MD
Immunotherapy encourages the recipient’s own immune response to destroy cancer cells, and current evidence suggests that immunotherapies may be most beneficial in early metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T is the first therapeutic cancer vaccine to be approved by both the US Food and Drug Administration and European Medicines Agency for the treatment of asymptomatic or minimally symptomatic mCRPC. Combining immunotherapy with other treatments may have potent anticancer effects; cytoreductive therapies can release tumor antigens and promote a proinflammatory environment that could augment immunotherapies. However, some cytoreductive agents or coadministered drugs may be immunosuppressive. Understanding these interactions between different mCRPC treatment modalities may offer further potential to improve patient outcomes.
From the President’s Desk
Juan A. Reyna, MD
Shared Medical Appointments in Urology
Jonathan Rubenstein, MD
Highlights From the 2014 American Urological Association Annual Meeting, May 16-21, 2014, Orlando, FL
Best of the 2014 AUA Annual Meeting
Adam J.M. Kern, MD, Alan W. Partin, MD, PhD, Ellen Shapiro, MD, FACS, FAAP
Occult Renal Cell Carcinoma Manifesting as Nasal Mass and Epistaxis
Janak Singh, MCh (Urology), Vishwas Baheti, MCh (Urology), Sher Singh Yadav, MCh (Urology), Rajeev Mathur, MCh (Urology)
The authors report a case of metastatic renal cell carcinoma presenting with right nasal cavity mass and epistaxis, followed by a brief review of the relevant literature.
Urethral Duplication in a 15-Year-Old: Case Report With Review of the Literature
Mayank Baid, MBBS, MS, Arindam Dutta, MS, MCh (Urology)
Urethral duplication is a rare congenital malformation mainly affecting men and boys. Although a number of theories have been proposed to describe this condition, the actual mechanism of this disorder is still not clear. This article highlights a case of urethral duplication in a 15-year-old boy.